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Acts as fundamental tool for analyzing gene function
For stem cell culture applications
For cortical stem cell expansion and differentiation into neurons, astrocytes and oligodendrocytes
Used for pharmacological testing
derived from murine strain C57/BL6J are selected for high targeting efficiency and proven germ line transmission.
characterized in studies of dopamine biosynthesis, neurotoxicity and used as a dopaminergic neuron model for in vitro and in vivo studies.